Accelerate Pharmaceutical Drug Discovery and Clinical Trials

A unique solution for accelerating the research of pharmaceutical companies pursuing precision drug discovery and clinical trials, drawing on the world’s largest international neuroscientific database, as well as our International Study to Predict Optimized Treatment for Depression (iSPOT-D).

Data Licensing


Total Brain’s international neuroscientific database is comprised of more than 1.3M standardized datasets which integrate complementary brain measures including cognitive performance, questionnaires, brain training, genomics, EEG and structural and functional MRI data.

Complementing this dataset is Total Brain’s iSPOT-D data, the largest study of its kind in depression which has been published in 55 peer-reviewed publications. The study has identified objective indicators of treatment response in more than 1,700 depressed individuals using a range of clinical measures, including:


  • Genetics (850,000 SNPs)
  • A battery of cognitive tests
  • Electroencephalogram (EEG)
  • Event related potentials (ERP)
  • Magnetic resonance imaging (MRI)
  • Diffusion tensor imaging (DTI)
  • Functional magnetic resonance imaging (FMRI)
  • Mainstream clinical assessments

These datasets can be licensed in whole, or in part, to support your companies’ clinical studies and precision drug development efforts.

Software Licensing


Total Brain’s clinically validated, digital assessment enables monitoring of cognitive and emotional functioning via 12 brain capacities, with integrated clinical screenings for 7 mental conditions like Addiction (CAGE-AID), Depression (PHQ-9), Anxiety (GAD7) and PTSD (PC-PTSD-5), among others.

12 Brain Capacities

Risk of 7 Mental Conditions



Screening questions

Symptom check

The assessment is designed to be repeated monthly, with results feeding a clinician dashboard to provide ongoing, objective patient data during clinical trials. Total Brain’s clinical support dashboard:

  • Monitors risk and capacity trends for patients
  • Flags for newly identified risk or changes from previous assessment
  • Visualizes patient progress over time
  • Helps assess overall outcomes via aggregate patient analytics

How Can Total Brain Help You?

Total Brain offers impactful benefits for companies, populations, providers and precision medicine.


Improve productivity and reduce mental health care costs.


Objectively monitor and accelerate your patients' full recovery.


Offer constituents a cutting-edge mental health and brain performance platform.

Precision Medicine

Accelerate pharmaceutical drug discovery and clinical trials.

Learn More

Schedule a meeting with a member of our team to learn how Total Brain can help you accelerate pharmaceutical drug discovery and clinical trials.

Book a Meeting